Research and analysis
NOIDs causative agents: week 22 (week ending 5 June 2022)
Updated 16 January 2023
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NOIDs weekly report
Laboratories in England have a statutory duty to notify the UK Health Security Agency of the identification of the following causative agents:
- Bacillus anthracis
- Bacillus cereus
- Bordetella pertussis
- Borrelia spp
- Brucella spp
- Burkholderia mallei
- Burkholderia pseudomallei
- Campylobacter spp
- Carbapenemase-producing Gram-negative bacteria
- Chikungunya virus
- Chlamydophila psittaci
- Clostridium botulinum
- Clostridium perfringens
- Clostridium tetani
- Corynebacterium diphtheriae
- Corynebacterium ulcerans
- Coxiella burnetii
- Crimean-Congo haemorrhagic fever virus
- Cryptosporidium spp
- Dengue virus
- Ebola virus
- Entamoeba histolytica
- Escherichia coli O 157
- Francisella tularensis
- Giardia lamblia
- Guanarito virus
- Haemophilus influenzae (invasive)
- Hanta virus
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D
- Hepatitis E
- Influenza virus
- Junin virus
- Kyasanur
- Forest disease virus
- Lassa virus
- Legionella spp
- Leptospira interrogans
- Listeria monocytogenes
- Machupo virus
- Marburg virus
- Measles virus
- Mumps virus
- Mycobacterium tuberculosis complex
- Neisseria meningitidis
- Omsk haemorrhagic fever virus
- Plasmodium falciparum
- Plasmodium knowlesi
- Plasmodium malariae
- Plasmodium ovale
- Plasmodium vivax
- Polio virus
- Rabies virus
- Rickettsia spp
- Rift Valley fever virus
- Rubella virus
- Sabia virus
- Salmonella spp
- SARS Coronavirus
- Shigella spp
- Streptococcus group A (invasive)
- Streptococcus pneumoniae (invasive)
- Varicella zoster virus
- Variola virus
- Vibrio cholerae
- West Nile virus
- Yellow fever virus
- Yersinia pestis
Statutory notifications of causative agents, grouped by root organism
Totals for the current week compared to the previous 5.
| Week notification received | 2022/17 | 2022/18 | 2022/19 | 2022/20 | 2022/21 | 2022/22 |
|---|---|---|---|---|---|---|
| Bacillus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Bacillus cereus | 15 | 28 | 16 | 15 | 19 | 12 |
| Bordetella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Bordetella pertussis | 4 | 1 | - | - | - | - |
| Borrelia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Borrelia burgdorferi | 11 | 14 | 13 | 10 | 16 | 16 |
| Borrelia sp | 1 | 1 | 1 | - | - | 1 |
| Brucella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Brucella melitensis | - | - | - | - | - | 1 |
| Burkholderia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Burkholderia pseudomallei | - | - | - | 1 | - | - |
| Campylobacter | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Campylobacter coli | 19 | 18 | 20 | 29 | 23 | 21 |
| Campylobacter fetus | - | - | 2 | 2 | 1 | - |
| Campylobacter jejuni | 301 | 199 | 261 | 331 | 355 | 245 |
| Campylobacter lari | 1 | - | - | 1 | - | - |
| Campylobacter other named | - | - | - | 1 | - | 1 |
| Campylobacter sp | 826 | 642 | 877 | 1,197 | 1,073 | 851 |
| Campylobacter upsaliensis | 1 | - | 1 | - | - | - |
| Campylobacter ureolyticus (bacteroides corrodens) | - | 2 | 1 | 1 | 2 | - |
| Chikungunya virus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Chikungunya virus | - | 1 | 1 | - | - | - |
| Clostridium | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Clostridium perfringens | 25 | 41 | 35 | 30 | 35 | 20 |
| Coronavirus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Coronavirus | 56 | 49 | 66 | 51 | 70 | 38 |
| Human coronavirus 229e | 2 | - | - | - | - | - |
| Human coronavirus hku1 | - | - | 1 | - | - | - |
| SARS coronavirus | 1 | - | - | - | 1 | - |
| SARS-CoV-2 antibody indeterminate | 173 | 75 | 98 | 115 | 122 | 49 |
| SARS-CoV-2 antibody void | 17 | 70 | 72 | 36 | 33 | 27 |
| SARS-CoV-2 coronavirus (COVID-19) | 70,577 | 61,608 | 52,617 | 42,734 | 35,659 | 40,248 |
| SARS-CoV-2 coronavirus (COVID-19) indeterminate | 1,212 | 1,041 | 854 | 934 | 966 | 748 |
| SARS-CoV-2 IgG antibody negative | 809 | 750 | 566 | 658 | 581 | 305 |
| SARS-CoV-2 IgG antibody positive | 2,497 | 2,085 | 2,073 | 1,910 | 1,348 | 747 |
| SARS-CoV-2 IgM antibody negative | 13 | 8 | 30 | 13 | 15 | 2 |
| SARS-CoV-2 IgM antibody positive | 4 | 2 | 10 | 2 | 4 | - |
| SARS-CoV-2 total antibody negative | 1,051 | 710 | 1,189 | 681 | 519 | 276 |
| SARS-CoV-2 total antibody positive | 3,511 | 2,193 | 2,680 | 2,089 | 1,619 | 1,054 |
| Corynebacterium | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Corynebacterium diphtheriae | 3 | - | 4 | - | 1 | - |
| Corynebacterium ulcerans | - | - | - | - | 1 | - |
| Coxiella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Coxiella burnetii | 1 | - | - | 1 | - | - |
| Cryptosporidium | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Cryptosporidium cuniculus | - | - | - | - | 1 | - |
| Cryptosporidium hominis | 3 | 1 | - | - | 2 | - |
| Cryptosporidium parvum | 85 | 50 | 39 | 53 | 21 | 7 |
| Cryptosporidium sp | 34 | 26 | 17 | 23 | 29 | 25 |
| Cryptosporidium ubiquitum | - | 1 | - | - | - | - |
| Entamoeba | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Entamoeba histolytica | 2 | 1 | 1 | 1 | 1 | 2 |
| Escherichia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Escherichia coli O 157 | 11 | 4 | 10 | 9 | 4 | 4 |
| Flaviviruses | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Dengue virus | - | 2 | 2 | - | 2 | - |
| Giardia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Giardia lamblia | - | - | 2 | 1 | 2 | 2 |
| Haemophilus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Haemophilus influenzae | 70 | 40 | 33 | 53 | 62 | 46 |
| Hepatitis viruses | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Hepatitis A | 11 | 6 | 15 | 12 | 9 | 4 |
| Hepatitis B | 177 | 203 | 235 | 181 | 209 | 103 |
| Hepatitis C | 270 | 312 | 308 | 361 | 351 | 296 |
| Hepatitis D | 3 | 2 | 6 | 3 | 2 | - |
| Hepatitis E | 19 | 29 | 29 | 34 | 34 | 19 |
| Influenza virus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Influenza A | 643 | 554 | 519 | 387 | 214 | 168 |
| Influenza B | 32 | 16 | 28 | 27 | 21 | 21 |
| Influenza indeterminate | 6 | - | - | 1 | - | - |
| Influenza ungrouped | 12 | 8 | 3 | 12 | 12 | 1 |
| Legionella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Legionella longbeachae | - | 1 | - | - | - | - |
| Legionella other named | - | 1 | - | - | - | 1 |
| Legionella pneumophila | 10 | 2 | 2 | 6 | 5 | 2 |
| Legionella sp | 1 | - | 3 | 1 | 2 | 1 |
| Listeria | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Listeria monocytogenes | 1 | 4 | 1 | 2 | 5 | 2 |
| Mycobacterium | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Mycobacterium tuberculosis | 69 | 63 | 63 | 63 | 65 | 44 |
| Neisseria | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Neisseria meningitidis | 6 | 12 | 6 | 19 | 14 | 11 |
| Paramyxoviruses | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Measles virus | 1 | - | - | - | - | 1 |
| Mumps virus | 2 | 2 | 2 | - | - | 2 |
| Plasmodium | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Plasmodium falciparum | 4 | 2 | - | 1 | 1 | 1 |
| Plasmodium ovale | 1 | - | - | - | - | - |
| Polyomavirus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Polyomavirus BK | 34 | 23 | 36 | 38 | 46 | 26 |
| Polyomavirus JC | 4 | 1 | 6 | 2 | 1 | 2 |
| Rickettsia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Rickettsia sp | - | 1 | - | - | - | - |
| Rickettsia spotted fever | - | 1 | - | - | - | - |
| Rubella virus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Rubella virus | 7 | 1 | - | 4 | 8 | - |
| Salmonella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Other salmonellas | 52 | 54 | 53 | 44 | 26 | 9 |
| Salmonella enteritidis | 42 | 24 | 26 | 20 | 13 | - |
| Salmonella infantis | 8 | - | - | 11 | - | 6 |
| Salmonella newport | - | - | 5 | 5 | - | - |
| Salmonella oranienburg | 6 | 6 | - | - | - | - |
| Salmonella sp | 17 | 13 | 6 | 72 | 132 | 99 |
| Salmonella typhi and paratyphi | 17 | 19 | 9 | 22 | 15 | 13 |
| Salmonella typhimurium | 32 | 38 | 24 | 32 | 20 | - |
| Shigella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Shigella boydii | 1 | - | 5 | 1 | - | - |
| Shigella dysenteriae | 1 | 1 | - | - | - | - |
| Shigella flexneri | 21 | 16 | 12 | 15 | 10 | 7 |
| Shigella sonnei | 24 | 13 | 21 | 22 | 11 | 12 |
| Shigella sp | 56 | 37 | 35 | 47 | 45 | 29 |
| Streptococcus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Streptococcus group A | 76 | 52 | 59 | 58 | 57 | 39 |
| Streptococcus pneumoniae | 96 | 95 | 80 | 70 | 91 | 81 |
| Vibrio | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Vibrio cholerae | - | 2 | - | 2 | 1 | - |
Carbapenemase-producing Enterobacterales (CPE)*
Please note: The numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.
| Week notification received | 2022/17 | 2022/18 | 2022/19 | 2022/20 | 2022/21 | 2022/22 | |
|---|---|---|---|---|---|---|---|
| Citrobacter | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Citrobacter spp | NDM | 1 | - | 1 | - | 1 | - |
| Ìý | OXA48 | - | - | 1 | - | - | - |
| Enterobacter | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Enterobacter cloacae complex | IMP | 1 | - | - | - | - | - |
| Ìý | KPC | - | 1 | 3 | 4 | - | - |
| Ìý | NDM | 2 | - | 1 | - | - | - |
| Ìý | OXA48 | 1 | - | 1 | - | - | - |
| Escherichia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Escherichia coli | KPC | 2 | 1 | 4 | 4 | - | - |
| Ìý | NDM | 6 | 1 | 4 | 3 | 3 | - |
| Ìý | OXA48 | 7 | 3 | 6 | 3 | 2 | - |
| Klebsiella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Klebsiella aerogenes | OXA48 | - | - | - | 1 | - | - |
| Klebsiella oxytoca | KPC | - | - | - | 2 | - | - |
| Ìý | OXA48 | 1 | - | - | - | - | - |
| Klebsiella pneumoniae | IMP | - | 1 | - | - | - | - |
| Ìý | KPC | 3 | 4 | 3 | 3 | 7 | - |
| Ìý | NDM | 3 | 1 | 1 | 5 | - | 1 |
| Ìý | OXA48 | 5 | 3 | 6 | 4 | 4 | 1 |
| Ìý | Other | 1 | - | 1 | 2 | - | - |
| Other klebsiella spp | KPC | - | - | - | - | 1 | - |
| Leclercia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Leclercia adecarboxylata | KPC | - | 1 | - | - | - | - |
| Providencia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Providencia stuartii | NDM | - | - | - | 1 | - | - |
Other carbapenemase-producing Gram-negative organisms*
Please note: The numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit
| Week notification received | 2022/17 | 2022/18 | 2022/19 | 2022/20 | 2022/21 | 2022/22 | |
|---|---|---|---|---|---|---|---|
| Acinetobacter | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Acinetobacter baumannii | IMP | - | - | - | 1 | - | - |
| Pseudomonas | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Pseudomonas aeruginosa | IMP | 1 | - | - | 1 | - | - |
| Ìý | NDM | - | 1 | - | - | - | - |
| Ìý | VIM | - | - | - | - | 1 | - |
| Ìý | Other | - | 1 | 2 | 1 | 2 | 2 |
| Pseudomonas putida group | Other | - | 1 | - | - | - | - |
*for all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.